BDBM50503147 CHEMBL4435232

SMILES CCCc1nc2[nH]c(C)c(NS(=O)(=O)c3ccc(cc3)C3CCCCC3)c(=O)n2n1

InChI Key InChIKey=OKXCVUICUUOADN-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50503147   

TargetGlutamate receptor ionotropic, NMDA 2C(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503147(CHEMBL4435232)
Affinity DataEC50:  6.60E+3nMAssay Description:Positive allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503147(CHEMBL4435232)
Affinity DataEC50:  6.70E+3nMAssay Description:Positive allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503147(CHEMBL4435232)
Affinity DataEC50:  1.57E+4nMAssay Description:Positive allosteric modulation of GluN2B receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Bristol

Curated by ChEMBL
LigandPNGBDBM50503147(CHEMBL4435232)
Affinity DataEC50:  3.20E+3nMAssay Description:Positive allosteric modulation of GluN2A receptor (unknown origin) expressed in xenopus laevis oocytes assessed as increase in glycine-induced channe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed