BDBM50502570 CHEMBL4450285

SMILES ONC(=O)c1ccc(NC(=O)CCC2N(Cc3ccccc3)C(=O)N(C2=O)c2ccc(Cl)cc2)cc1

InChI Key InChIKey=DARFUQJSJROALF-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50502570   

TargetHistone deacetylase 6(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50502570(CHEMBL4450285)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-LeuGlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50502570(CHEMBL4450285)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of HDAC5 (unknown origin) using Ac-LeuGlyLys(tfa)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50502570(CHEMBL4450285)
Affinity DataIC50: 114nMAssay Description:Inhibition of HDAC10 (unknown origin) using Ac-ArgThr- Lys(Ac)Lys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50502570(CHEMBL4450285)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of HDAC9 (unknown origin) using Ac-LeuGlyLys(tfa)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50502570(CHEMBL4450285)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using Ac-LeuGlyLys(tfa)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50502570(CHEMBL4450285)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of HDAC4 (unknown origin) using Ac-LeuGlyLys(tfa)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50502570(CHEMBL4450285)
Affinity DataIC50: 96nMAssay Description:Inhibition of HDAC3 (unknown origin) using Ac-LeuGlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50502570(CHEMBL4450285)
Affinity DataIC50: 203nMAssay Description:Inhibition of HDAC2 (unknown origin) using Ac-LeuGlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50502570(CHEMBL4450285)
Affinity DataIC50: 111nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-LeuGlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50502570(CHEMBL4450285)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of HDAC7 (unknown origin) using Ac-LeuGlyLys(tfa)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50502570(CHEMBL4450285)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HDAC11 (unknown origin) using Ac-LeuGlyLys(Ac)-AMC as substrate preincubated for 5 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed