BDBM50502328 CHEMBL4472444

SMILES O=C(Cc1coc2ccc3ccccc3c12)Oc1ccc(cc1)-c1nnco1

InChI Key InChIKey=UPFIGKNEXDPWKJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50502328   

TargetATP-dependent Clp protease proteolytic subunit, mitochondrial(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50502328(CHEMBL4472444)
Affinity DataIC50: 4.44E+3nMAssay Description:Inhibition of human ClpP expressed in Escherichia coli SG1146 cells using N-acetyl-Trp-Leu-Ala-AMC as substrate incubated for 1 hr and measured at 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetATP-dependent Clp protease proteolytic subunit, mitochondrial(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM50502328(CHEMBL4472444)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of C-terminal recombinant human ClpP (57 to 277 amino acids) expressed in Escherichia coli Rosetta2 cells using Suc-Leu-Tyr-AMC as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed