BDBM50502295 CHEMBL4439128

SMILES COc1ccc(cc1OC)-c1cnc2[nH]cc(C#Cc3cccnc3)c2c1

InChI Key InChIKey=CJTVDIBZBUWIFC-UHFFFAOYSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50502295   

TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502295(CHEMBL4439128)
Affinity DataIC50: 4nMAssay Description:Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502295(CHEMBL4439128)
Affinity DataIC50: 4nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502295(CHEMBL4439128)
Affinity DataIC50: 4nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502295(CHEMBL4439128)
Affinity DataKd:  4nMAssay Description:Binding affinity to AAK1 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
Ku Leuven

Curated by ChEMBL
LigandPNGBDBM50502295(CHEMBL4439128)
Affinity DataIC50: 4nMAssay Description:Inhibition of AAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed