BDBM50501946 CHEMBL4437401

SMILES CN[C@@H](C)C(=O)N[C@@H](Cc1ccc(OS(F)(=O)=O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCc2c1cccc2F

InChI Key InChIKey=VYJTVHQPRHYCQH-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50501946   

TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501946(CHEMBL4437401)
Affinity DataIC50: 28nMAssay Description:Displacement of biotinylated AVPF from N-terminal His tagged recombinant human XIAP-BIR3 domain (253 to 347 residues) expressed in Escherichia coli B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501946(CHEMBL4437401)
Affinity DataIC50: 63nMAssay Description:Displacement of biotinylated AVPF from N-terminal His tagged recombinant human XIAP-BIR3 domain (253 to 347 residues) expressed in Escherichia coli B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed
LigandPNGBDBM50501946(CHEMBL4437401)
Affinity DataIC50: 24nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP1-BIR3 (258 to 363 residues) expressed in Escherichia coli incubated for 2 hrs without 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501946(CHEMBL4437401)
Affinity DataIC50: 63nMAssay Description:Inhibition of N-terminal His-tagged human XIAP-BIR3 (253 to 347 residues) expressed in Escherichia coli BL21-Gold(DE3) pLysS incubated for 2 hrs with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50501946(CHEMBL4437401)
Affinity DataIC50: 24nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP1-BIR3 (258 to 363 residues) expressed in Escherichia coli incubated for 2 hrs without 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50501946(CHEMBL4437401)
Affinity DataIC50: 47nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP2-BIR3 (244 to 349 residues) expressed in Escherichia coli incubated for 2 hrs after 6 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50501946(CHEMBL4437401)
Affinity DataIC50: 40nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP2-BIR3 (244 to 349 residues) expressed in Escherichia coli incubated for 2 hrs without 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50501946(CHEMBL4437401)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP1-BIR3 (258 to 363 residues) expressed in Escherichia coli incubated for 2 hrs after 6 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501946(CHEMBL4437401)
Affinity DataIC50: 28nMAssay Description:Inhibition of N-terminal His-tagged human XIAP-BIR3 (253 to 347 residues) expressed in Escherichia coli BL21-Gold(DE3) pLysS incubated for 2 hrs afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50501946(CHEMBL4437401)
Affinity DataIC50: 47nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP2-BIR3 (244 to 349 residues) expressed in Escherichia coli incubated for 2 hrs after 6 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501946(CHEMBL4437401)
Affinity DataIC50: 28nMAssay Description:Inhibition of N-terminal His-tagged human XIAP-BIR3 (253 to 347 residues) expressed in Escherichia coli BL21-Gold(DE3) pLysS incubated for 2 hrs afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase XIAP(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50501946(CHEMBL4437401)
Affinity DataIC50: 63nMAssay Description:Inhibition of N-terminal His-tagged human XIAP-BIR3 (253 to 347 residues) expressed in Escherichia coli BL21-Gold(DE3) pLysS incubated for 2 hrs with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50501946(CHEMBL4437401)
Affinity DataIC50: 40nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP2-BIR3 (244 to 349 residues) expressed in Escherichia coli incubated for 2 hrs without 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50501946(CHEMBL4437401)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal 6x-His-tagged recombinant human cIAP1-BIR3 (258 to 363 residues) expressed in Escherichia coli incubated for 2 hrs after 6 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed