BDBM50501451 CHEMBL4078889

SMILES COc1ccc(Cn2cnc3sc4CC(CCc4c3c2=O)NC2CCCC2)c2ccccc12

InChI Key InChIKey=VNYNNOWTPOEWDU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50501451   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50501451(CHEMBL4078889)
Affinity DataIC50: 730nMAssay Description:Inhibition of recombinant human C-terminal His-tagged SIRT2 (50 to 389 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50501451(CHEMBL4078889)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged SIRT3 (101 to 399 residues) expressed in Escherichia coli using p53 derived (379 to 382 residue...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50501451(CHEMBL4078889)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged SIRT1 (1 to 747 end residues) expressed in Escherichia coli using p53 derived (379 to 382 resid...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed