BDBM50500858 CHEMBL3800016

SMILES CCOc1ccc(cc1)-c1cc(nn1-c1ccccc1)C(O)=O

InChI Key InChIKey=QHXBYJRUEXSIEL-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50500858   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50500858(CHEMBL3800016)
Affinity DataKi:  3.26E+3nMAssay Description:Displacement of FAM-p53TAD peptide from N-terminal 8x His-tagged human MDM2 (25 to 108 residues) expressed in Escherichia coli BL21 (DE3) after 30 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50500858(CHEMBL3800016)
Affinity DataKi:  3.80E+3nMAssay Description:Displacement of FAM-Bid peptide from N-terminal 8x His-tagged MCl-1 (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
Dalian University of Technology

Curated by ChEMBL
LigandPNGBDBM50500858(CHEMBL3800016)
Affinity DataKi:  6.09E+3nMAssay Description:Displacement of FAM-Bid peptide from N-terminal 8x His-tagged Bcl-2 (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed