BDBM50500352 CHEMBL3746665::US11066363, Compound 17

SMILES CCc1cc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2cc1N1CCC(CC1)N(C)C

InChI Key InChIKey=LSTKGNJVVPYVIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500352   

LigandPNGBDBM50500352(CHEMBL3746665 | US11066363, Compound 17)
Affinity DataIC50: 2nMAssay Description:Inhibition of wild type EML4-ALK (unknown origin) expressed in mouse Ba/F3 cells assessed as cell viability after 72 hrs by MTS assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSRSF protein kinase 1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50500352(CHEMBL3746665 | US11066363, Compound 17)
Affinity DataIC50: 103nMAssay Description:SRPK1 Inhibitory Activities of the Compounds.More data for this Ligand-Target Pair
In DepthDetails
US Patent