BDBM50499377 CHEMBL3735194

SMILES NC(=O)c1cnc2ccc(cc2c1Nc1ccc(N2CCNCC2)c(c1)C(F)(F)F)-c1cnc2ccccc2c1

InChI Key InChIKey=HHZIEIHPROHCFW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499377   

TargetSerine/threonine-protein kinase mTOR(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50499377(CHEMBL3735194)
Affinity DataIC50: 14nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide as substrate after 1 hr by lance ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50499377(CHEMBL3735194)
Affinity DataIC50: 14nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed