BDBM50498037 CHEMBL3329535
SMILES O=C(C1CC=CC1)N1CC2CC(C1)N2
InChI Key InChIKey=LFBLWBXTTPQJNY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50498037
Affinity DataEC50: 1.70E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity isoform transfected in SH-EP1 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-2/beta-3(Human)
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataEC50: 1.90E+3nMAssay Description:Agonist activity at human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 6.60E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR transfected in SH-EP1 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Displacement of [3H] nicotine from human alpha4beta2 nAChR transfected in SH-EP1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-2/beta-3(Human)
Targacept
Curated by ChEMBL
Targacept
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [3H]epibatidine from human alpha6/alpha3beta2beta3 nAChR transfected in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair