BDBM50497304 CHEMBL3335453

SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCCC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSSC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC2=O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(C)=O)C(C)C

InChI Key InChIKey=FMFQQQHCFDLITQ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50497304   

TargetTranscriptional enhancer factor TEF-1(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50497304(CHEMBL3335453)
Affinity DataIC50: 42nMAssay Description:Inhibition of YAP/ GST-TEAD1 (unknown origin) interaction by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTranscriptional enhancer factor TEF-1(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50497304(CHEMBL3335453)
Affinity DataKd:  18nMAssay Description:Inhibition of YAP/ GST-TEAD1 interaction in human Bel-7404 cells by GST pull-down assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed