BDBM50497293 CHEMBL3335451

SMILES [H][C@@]12CCCN1C(=O)[C@H](CCCC)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSSC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC2=O)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(N)=O)NC(=O)[C@H](CCSC)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(C)=O)C(C)C

InChI Key InChIKey=JLFVYIWUQHPMTB-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50497293   

TargetTranscriptional enhancer factor TEF-1(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50497293(CHEMBL3335451)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of YAP/ GST-TEAD1 (unknown origin) interaction by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTranscriptional enhancer factor TEF-1(Human)
Roche Innovation Center Shanghai

Curated by ChEMBL
LigandPNGBDBM50497293(CHEMBL3335451)
Affinity DataKd:  211nMAssay Description:Inhibition of YAP/ GST-TEAD1 interaction in human Bel-7404 cells by GST pull-down assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed