BDBM50495830 CHEMBL1530518

SMILES COC(=O)Nc1nc2cc(ccc2[nH]1)-c1nnc(O)c2ccccc12

InChI Key InChIKey=RUTAYAFBXACDGP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50495830   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Yale University

Curated by ChEMBL
LigandPNGBDBM50495830(CHEMBL1530518)
Affinity DataIC50: 1.42E+5nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR using methylenetetrahydrofolate/dUMP as sustrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Yale University

Curated by ChEMBL
LigandPNGBDBM50495830(CHEMBL1530518)
Affinity DataIC50: 1.39E+5nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR by Michaelis-Menten plot analysis in presence of bovine serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Yale University

Curated by ChEMBL
LigandPNGBDBM50495830(CHEMBL1530518)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR using methylenetetrahydrofolate/dUMP as sustrate preincubated for 10 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed