BDBM50495691 CHEMBL3116308

SMILES OP(O)(=O)C(Cc1ccc(Cl)c(Cl)c1)(Cc1ccc(Cl)c(Cl)c1)P(O)(O)=O

InChI Key InChIKey=HHRAQYLQCIWYSQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50495691   

TargetIntegrase(Human immunodeficiency virus type 1)
Lomonosov Moscow State University

Curated by ChEMBL
LigandPNGBDBM50495691(CHEMBL3116308)
Affinity DataIC50: 5.00E+5nMAssay Description:Displacement of [32P]-labeled U5B/U5A DNA from HIV-1 integrase expressed in Escherichia coli in presence of Mn2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Lomonosov Moscow State University

Curated by ChEMBL
LigandPNGBDBM50495691(CHEMBL3116308)
Affinity DataIC50: 800nMAssay Description:Inhibition of HIV-1 integrase expressed in Escherichia coli using [32P]-labeled U5B/U5A DNA as substrate assessed as inhibition of 3'-processing reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Lomonosov Moscow State University

Curated by ChEMBL
LigandPNGBDBM50495691(CHEMBL3116308)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of HIV-1 integrase expressed in Escherichia coli using [32P]-labeled U5B-2/U5A DNA as substrate assessed as inhibition of strand transfer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Lomonosov Moscow State University

Curated by ChEMBL
LigandPNGBDBM50495691(CHEMBL3116308)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [32P]-labeled U5B/U5A DNA from HIV-1 integrase expressed in Escherichia coli in presence of Mg2+More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Lomonosov Moscow State University

Curated by ChEMBL
LigandPNGBDBM50495691(CHEMBL3116308)
Affinity DataIC50: 800nMAssay Description:Inhibition of HIV-1 integrase expressed in Escherichia coli using [32P]-labeled U5B-2/U5A DNA as substrate assessed as inhibition of strand transfer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Lomonosov Moscow State University

Curated by ChEMBL
LigandPNGBDBM50495691(CHEMBL3116308)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of HIV-1 integrase expressed in Escherichia coli using [32P]-labeled U5B/U5A DNA as substrate assessed as inhibition of 3'-processing reac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed