BDBM50495472 CHEMBL3108952

SMILES N[C@@H]1C[C@H]1c1ccc(NC(=O)c2ccc(O)c3ncccc23)cc1

InChI Key InChIKey=IOISINYXKTVMBM-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50495472   

TargetLysine-specific demethylase 5C(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50495472(CHEMBL3108952)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant JARID1C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50495472(CHEMBL3108952)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of FIH (unknown origin) by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50495472(CHEMBL3108952)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of PHD2 (unknown origin) by mass spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 2A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50495472(CHEMBL3108952)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of recombinant FBXL11 (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 4C(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50495472(CHEMBL3108952)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant JMJD2C (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50495472(CHEMBL3108952)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of recombinant JMJD3 (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50495472(CHEMBL3108952)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant His-tagged LSD1 (171 to 836) assessed as hydrogen peroxide formation after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50495472(CHEMBL3108952)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of human recombinant MAO-B expressed in Pichia pastoris using benzylamine as substrate after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50495472(CHEMBL3108952)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in Pichia pastoris using kynuramine as substrate after 5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 3A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50495472(CHEMBL3108952)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of recombinant JMJD1A (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50495472(CHEMBL3108952)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of recombinant JMJD2E (unknown origin) incubated for 15 mins prior to substrate addition by AlphaScreen methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed