BDBM50492832 CHEMBL2413298

SMILES Cc1ccc(OCCCCN(Cc2ccc(\C=C\C(=O)NO)o2)Cc2ccccc2)cc1

InChI Key InChIKey=CVXPSEOAGUXFLC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50492832   

TargetHistone deacetylase 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50492832(CHEMBL2413298)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of human recombinant HDAC4 using p53 residues 379-382 (RHKKAc) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50492832(CHEMBL2413298)
Affinity DataIC50: 4.73E+3nMAssay Description:Inhibition of human recombinant HDAC1 using p53 residues 379-382 (RHKKAc) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50492832(CHEMBL2413298)
Affinity DataIC50: 550nMAssay Description:Inhibition of human recombinant HDAC6 using p53 residues 379-382 (RHKKAc) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50492832(CHEMBL2413298)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of HDAC in human HeLa cell extract using Fluor deLys as substrate by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed