BDBM50492483 CHEMBL2402940

SMILES CCN\C1=N\C[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](CN1)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(N)=O

InChI Key InChIKey=DQTLFRUYXNXMTE-UHFFFAOYSA-N

Data  2 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50492483   

TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492483(CHEMBL2402940)
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492483(CHEMBL2402940)
Affinity DataEC50:  1.23E+3nMAssay Description:Agonist activity at mu opioid receptor in rat brain membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins in presence of GDPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492483(CHEMBL2402940)
Affinity DataEC50:  1.23E+3nMAssay Description:Agonist activity at mu opioid receptor in rat brain membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins in presence of GDPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492483(CHEMBL2402940)
Affinity DataIC50: 363nMAssay Description:Displacement of [3H]-DIDI from delta opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492483(CHEMBL2402940)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492483(CHEMBL2402940)
Affinity DataKi:  263nMAssay Description:Displacement of [3H]-DIDI from delta opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed