BDBM50492365 CHEMBL2403860

SMILES CC(C)(O)c1nc2cc(Cl)ccc2n1[C@@H]1CC[C@@H](CC1)NCC1Cc2ccc(cc2C1)C(F)(F)F

InChI Key InChIKey=HGTXQPAMHYVMBW-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50492365   

TargetMelanin-concentrating hormone receptor 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50492365(CHEMBL2403860)
Affinity DataIC50: 230nMAssay Description:Displacement of [125I]MCH peptide from human MCHR1 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50492365(CHEMBL2403860)
Affinity DataEC50:  480nMAssay Description:Antagonist activity at human MCHR1 expressed in CHOK1 cells assessed as inhibition of MCH/forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed