BDBM50492031 CHEMBL2392839

SMILES CCOC1CCN(C1)C(=O)[C@H]1CC[C@@H](CC1)Nc1nccc(n1)-n1ccc2c(cccc12)N1CCC(CC1)S(C)(=O)=O

InChI Key InChIKey=FVPQKFPGPOAQPF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50492031   

TargetMitogen-activated protein kinase 10/8/9(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50492031(CHEMBL2392839)
Affinity DataIC50: 420nMAssay Description:Inhibition of JNK-mediated c-Jun activation in TNFalpha-induced human SW1353 cells preincubated for 30 mins prior to TNFalpha treatment measured afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50492031(CHEMBL2392839)
Affinity DataIC50: 86nMAssay Description:Inhibition of human JNK2alpha2 using GST-tagged ATF2 as substrate preincubated for 10 mins prior to substrate addition measured after 30 mins by micr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50492031(CHEMBL2392839)
Affinity DataIC50: 12nMAssay Description:Inhibition of human JNK1alpha1 using GST-tagged ATF2 as substrate preincubated for 10 mins prior to substrate addition measured after 30 mins by micr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed