BDBM50491090 CHEMBL2377109

SMILES COc1ccccc1Cc1cc2c(N)nc(nc2s1)-c1ccc(C)o1

InChI Key InChIKey=YGURUQQTVSHGEJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50491090   

TargetAdenosine receptor A2a(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50491090(CHEMBL2377109)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to human adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAdenosine receptor A2a(Human)
Isf College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50491090(CHEMBL2377109)
Affinity DataKi:  11nMAssay Description:Antagonist activity at human adenosine A2a receptor expressed in CHOK1 cells assessed as inhibition of NECA/forskolin-induced cAMP accumulation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50491090(CHEMBL2377109)
Affinity DataKi:  122nMAssay Description:Antagonist activity at human adenosine A1 receptor expressed in CHOK1 cells assessed as inhibition of R-PIA/forskolin-induced cAMP accumulation incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed