BDBM50490813 CHEMBL2346911

SMILES C\C(CC[C@@H](O)C(C)=C)=C/COc1ccc2ccc(=O)oc2c1

InChI Key InChIKey=OWAQHJLCKMIPKB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50490813   

TargetNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50490813(CHEMBL2346911)
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1,10-phenanthroline-induced HIF1 activation incubated for 30 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetNADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50490813(CHEMBL2346911)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of mitochondrial ETC complex 1 in human T47D cells assessed as inhibition of 1% O2-induced HIF1 activation incubated for 30 mins prior to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Mouse)
R.C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50490813(CHEMBL2346911)
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of mouse brain MAO-BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Mouse)
R.C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50490813(CHEMBL2346911)
Affinity DataIC50: 0.00100nMAssay Description:Inhibition of mouse brain MAO-AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Mouse)
R.C. Patel Institute of Pharmaceutical Education and Research

Curated by ChEMBL
LigandPNGBDBM50490813(CHEMBL2346911)
Affinity DataIC50: 500nMAssay Description:Inhibition of mouse MAO-B preincubated for 15 mins followed by addition of kynuramine as substrate measured after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed