BDBM50485886 CHEMBL2180479

SMILES CCCC(C(O)=O)c1c(C)nc2ccc(Cl)cc2c1-c1ccccc1

InChI Key InChIKey=XRPUJSGGRFQZPJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50485886   

TargetIntegrase(Human immunodeficiency virus type 1)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50485886(CHEMBL2180479)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HIV1 His6-tagged integrase-human GST tagged LEDGF/p75 (373-442 residues) interaction after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50485886(CHEMBL2180479)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of LEDGF/p75-dependent full length HIV-1 integrase expressed in Escherichia coli BL21(DE3) cells preincubated for 1 hr further incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50485886(CHEMBL2180479)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of subunit exchanging activity of His and Flag-tagged HIV-1 integrase expressed in Escherichia coli BL21(DE3) cells after 2.5 hrs by HTRF ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed