BDBM50485836 CHEMBL2170478

SMILES Nc1ncnc2n(CCC3CCN(CC3)C(=O)[C@@H]3CCCN3)c(Sc3cc4OCOc4cc3Br)nc12

InChI Key InChIKey=PEHIYOQUUMHTNJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485836   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Myrexis

Curated by ChEMBL
LigandPNGBDBM50485836(CHEMBL2170478)
Affinity DataIC50: 190nMAssay Description:Inhibition of human HSP90 in HCT116 cells expressing Her2 gene assessed as degradation of Her2 after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Myrexis

Curated by ChEMBL
LigandPNGBDBM50485836(CHEMBL2170478)
Affinity DataIC50: 60nMAssay Description:Inhibition of human HSP90 using BODIPY labelled geldanamycin as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed