BDBM50485832 CHEMBL2170487

SMILES C[C@H](O)C(=O)N1CCC(CCn2c(Sc3cc4OCCOc4cc3Br)nc3c(N)ncnc23)CC1

InChI Key InChIKey=VJSOUGMQBHUKBW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485832   

TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Myrexis

Curated by ChEMBL
LigandPNGBDBM50485832(CHEMBL2170487)
Affinity DataIC50: 74nMAssay Description:Inhibition of human HSP90 in HCT116 cells expressing Her2 gene assessed as degradation of Her2 after 4 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Myrexis

Curated by ChEMBL
LigandPNGBDBM50485832(CHEMBL2170487)
Affinity DataIC50: 150nMAssay Description:Inhibition of human HSP90 using BODIPY labelled geldanamycin as substrate by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article
PubMed