BDBM50485362 CHEMBL2057226

SMILES CC(C)Cc1cc(CNC(=O)N2CCN(CC(=O)Nc3ccccc3Cl)CC2)nn1-c1ccccc1

InChI Key InChIKey=XHHMTZMVSPEWCP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485362   

TargetHistone acetyltransferase p300/Hypoxia-inducible factor 1-alpha(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50485362(CHEMBL2057226)
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibition of human C-terminal activation domain of HIF-1alpha/CH1 domain of GST-p300 interaction using F-786-826 by fluorescence polarization based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetCREB-binding protein/Histone acetyltransferase p300(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50485362(CHEMBL2057226)
Affinity DataIC50: 1.07E+5nMAssay Description:Inhibition of GST-tagged p300 (unknown origin)/CBP (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed