BDBM50484601 CHEMBL1939298

SMILES [H][C@@]12CNC[C@]1([H])CN(C2)c1cncc(n1)C(=O)Nc1cccc(OC(C)C)c1

InChI Key InChIKey=JFNIDOODFZIFIJ-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50484601   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50484601(CHEMBL1939298)
Affinity DataEC50: >1.00E+5nMAssay Description:Partial agonist activity at human nAChR alpha4beta2 receptor expressed in human HEK293 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50484601(CHEMBL1939298)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]cytisine from nAChR alpha4beta2 in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50484601(CHEMBL1939298)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]cytisine from nAChR alpha4beta2 in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed