BDBM50482725 CHEMBL1253951

SMILES CN(C)CCOc1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc2-c3[nH]ncc3CCc2c1

InChI Key InChIKey=KHZFXRDVTTTZPH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50482725   

TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50482725(CHEMBL1253951)
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of human full-length B-Raf V600E mutant expressed in baculovirus infected Sf9 cells after 45 mins by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50482725(CHEMBL1253951)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of B-Raf V600E mutant-mediated ERK1/2 phosphorylation in human WM266.4 cells after 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed