BDBM50482010 CHEMBL1090716

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)[nH]c34)cc2)n(Cc2ccccc2)n1

InChI Key InChIKey=XMRFQIBMKVNRGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50482010   

TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50482010(CHEMBL1090716)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of BRAF V600E mutant ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50482010(CHEMBL1090716)
Affinity DataIC50: 147nMAssay Description:Inhibition of human BRAF V600E mutant expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed