BDBM50481996 CHEMBL1090978

SMILES Cn1c2c(Oc3ccc(NC(=O)Nc4cc(nn4-c4cccnc4)C(C)(C)C)c4ccccc34)ccnc2[nH]c1=O

InChI Key InChIKey=JBNYIHPVUCADJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50481996   

TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50481996(CHEMBL1090978)
Affinity DataIC50: 100nMAssay Description:Inhibition of BRAF V600E mutant ERK phosphorylation in human WM266.4 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50481996(CHEMBL1090978)
Affinity DataIC50: 790nMAssay Description:Inhibition of human BRAF V600E mutant expressed in baculovirus systemMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed