BDBM50481904 CHEMBL1079641

SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)n1c2ccccc2c2ccc(OCC(O)=O)cc12

InChI Key InChIKey=YCQSFWKWOPQDGY-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50481904   

TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50481904(CHEMBL1079641)
Affinity DataEC50: >4.00E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as increase in amyloid beta38 production by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50481904(CHEMBL1079641)
Affinity DataIC50: 4.00E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta42 production by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50481904(CHEMBL1079641)
Affinity DataIC50: 4.00E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta40 production by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed