BDBM50481896 CHEMBL1081581

SMILES OC(=O)COc1ccc2c(c1)n(Cc1cccc(c1)C1(N=N1)C(F)(F)F)c1ccccc21

InChI Key InChIKey=SDBMDFMLMZZFKS-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50481896   

TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50481896(CHEMBL1081581)
Affinity DataEC50: >8.00E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as increase in amyloid beta38 production by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50481896(CHEMBL1081581)
Affinity DataIC50: 8.00E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta42 production by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50481896(CHEMBL1081581)
Affinity DataIC50: 8.00E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta40 production by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed