BDBM50481825 CHEMBL5277258

SMILES CC(C)C1=C(Nc2c(cnn2C1=O)C#N)c3cnn(c3)CCNC(=O)CCl

InChI Key InChIKey=RODFEBSPUBMOBA-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50481825   

TargetLysine-specific demethylase 5A(Human)
Ningbo University

Curated by ChEMBL
LigandPNGBDBM50481825(CHEMBL5277258)
Affinity DataIC50: 10nMAssay Description:Inhibition of KDM5A (unknown origin ) by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Ningbo University

Curated by ChEMBL
LigandPNGBDBM50481825(CHEMBL5277258)
Affinity DataIC50: 7nMAssay Description:Inhibition of KDM5B (unknown origin ) by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 5C(Human)
Ningbo University

Curated by ChEMBL
LigandPNGBDBM50481825(CHEMBL5277258)
Affinity DataIC50: 571nMAssay Description:Inhibition of KDM5C (unknown origin ) by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Ningbo University

Curated by ChEMBL
LigandPNGBDBM50481825(CHEMBL5277258)
Affinity DataIC50: 7nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysine-specific demethylase 5B(Human)
Ningbo University

Curated by ChEMBL
LigandPNGBDBM50481825(CHEMBL5277258)
Affinity DataIC50: 530nMAssay Description:Inhibition of KDM5B in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)