BDBM50480868 CHEMBL571500

SMILES COc1cc(NC(=O)c2ccc(cc2)-c2cc3ccccc3oc2=O)ccc1NC(=O)c1ccccc1Cl

InChI Key InChIKey=XQGRLBREQBQTBH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50480868   

TargetDNA-binding transcriptional activator DevR/DosR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Indian Institute of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50480868(CHEMBL571500)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of DevR region-dependent narK2 promoter activity in Mycobacterium tuberculosis H37Rv after 48 hrs by GFP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetDNA-binding transcriptional activator DevR/DosR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Indian Institute of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50480868(CHEMBL571500)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of DevR region-dependent Rv3134c promoter activity in Mycobacterium tuberculosis H37Rv after 48 hrs by GFP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetDNA-binding transcriptional activator DevR/DosR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Indian Institute of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50480868(CHEMBL571500)
Affinity DataIC50: 4.95E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis phosphorylated DevR binding to fdxA promoter DNA after 10 mins by EMSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetDNA-binding transcriptional activator DevR/DosR(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Indian Institute of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50480868(CHEMBL571500)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of DevR region-dependent hspX promoter activity in Mycobacterium tuberculosis H37Rv after 48 hrs by GFP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed