BDBM50479547 CHEMBL455138

SMILES [#6]-[#8]-c1ccc(cc1)-[#6](=O)\[#6]=[#6]-1\c2ccccc2-[#6](=O)-c2ccccc-12

InChI Key InChIKey=FPXJRYADJIOVFJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50479547   

TargetTubulin beta chain(Pig)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandPNGBDBM50479547(CHEMBL455138)
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]Colchicine from pig biotinylated tubulin after 2 hrs by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandPNGBDBM50479547(CHEMBL455138)
Affinity DataIC50: 520nMAssay Description:Inhibition of pig brain tubulin polymerization after 30 mins by turbidimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetTubulin beta chain(Pig)
Westphalian Wilhelms-University

Curated by ChEMBL
LigandPNGBDBM50479547(CHEMBL455138)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]paclitaxel from pig biotinylated tubulin after 2 hrs by SPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed