BDBM50472080 CHEMBL42618

SMILES Clc1ccc(cc1Cl)C(=O)N1CCC(CNCc2cccc(n2)-c2cccs2)CC1

InChI Key InChIKey=CKSMNIPCJNWJND-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50472080   

Target5-hydroxytryptamine receptor 1A(Human)
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50472080(CHEMBL42618)
Affinity DataEC50:  5.80nMAssay Description:In vitro effective concentration required to inhibit forskolin-stimulated cAMP levels in HA7 cells expressing human 5-HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50472080(CHEMBL42618)
Affinity DataKi:  1.40nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat cortex using [3H]8-OH-DPAT as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50472080(CHEMBL42618)
Affinity DataKi:  1.40nMAssay Description:Binding affinity for rat cortex 5-hydroxytryptamine 1A receptor, by displacement of 0.2 nM [3H]8-OH-DPAT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50472080(CHEMBL42618)
Affinity DataKi:  174nMAssay Description:Binding affinity towards Alpha-1 adrenergic receptor using prazosin as a radioligand in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Pierre Fabre Research Center

Curated by ChEMBL
LigandPNGBDBM50472080(CHEMBL42618)
Affinity DataKi:  288nMAssay Description:Binding affinity towards Dopamine receptor D2 in rat striatum using YM-09151-2 as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed