BDBM50470557 CHEMBL4290778

SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](COCc1ccccc1)C(=O)OCc1ccccc1

InChI Key InChIKey=PGTDWVFHKGDQFC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50470557   

TargetProteasome subunit beta type-5(Human)
New Mexico Institute of Mining and Technology

Curated by ChEMBL
LigandPNGBDBM50470557(CHEMBL4290778)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
New Mexico Institute of Mining and Technology

Curated by ChEMBL
LigandPNGBDBM50470557(CHEMBL4290778)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of yeast 20S proteasome beta2 subunit using SUC-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetmRNA cap guanine-N7 methyltransferase(Human)
New Mexico Institute of Mining and Technology

Curated by ChEMBL
LigandPNGBDBM50470557(CHEMBL4290778)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of yeast 20S proteasome beta1 subunit using fluorescent substrate pretreated for 30 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
New Mexico Institute of Mining and Technology

Curated by ChEMBL
LigandPNGBDBM50470557(CHEMBL4290778)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of 20S proteasome beta2 subunit in human Jurkat cell lysate using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
New Mexico Institute of Mining and Technology

Curated by ChEMBL
LigandPNGBDBM50470557(CHEMBL4290778)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human immunoproteasome beta5 subunit using Suc-RLR-AMC as substrate pretreated for 30 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2020
Entry Details Article
PubMed