BDBM50468558 CHEMBL4286889

SMILES S=C(Nc1ccccc1)N1N=C(CC1c1ccc2OCCOc2c1)c1cccs1

InChI Key InChIKey=DJWUWQKHGCJTLN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50468558   

TargetSerine/threonine-protein kinase B-raf(Mouse)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468558(CHEMBL4286889)
Affinity DataIC50: 7.83E+4nMAssay Description:Inhibition of mouse full length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50468558(CHEMBL4286889)
Affinity DataIC50: 5.21E+3nMAssay Description:Inhibition of recombinant human full length GST-tagged wild type BRAF expressed in baculovirus expression system using recombinant human full length ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed