BDBM50468262 CHEMBL4277903

SMILES Cc1cc(C)cc(NC(=N)Nc2ccccc2C(F)(F)F)c1

InChI Key InChIKey=DVIJFJSZZNOTLP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50468262   

TargetSerine/threonine-protein kinase PAK 1(Human)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50468262(CHEMBL4277903)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of PAK1 in human MCF7 cells transfected with constitutively active NH2-terminally truncated C1199 Tiam1 constructMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetRas-related C3 botulinum toxin substrate 1(Human)
Lodz University of Technology

Curated by ChEMBL
LigandPNGBDBM50468262(CHEMBL4277903)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Rac1 GTPase in human MDA-MB-231 cells assessed as inhibition of cell proliferation treated for 72 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed