BDBM50468246 CHEMBL4286374

SMILES Oc1cc(ccc1C(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1)C(F)(F)F

InChI Key InChIKey=WCOVFXVCWRMHFE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50468246   

TargetEpidermal growth factor receptor(Human)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50468246(CHEMBL4286374)
Affinity DataIC50: 120nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50468246(CHEMBL4286374)
Affinity DataIC50: 96nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Ain Shams University

Curated by ChEMBL
LigandPNGBDBM50468246(CHEMBL4286374)
Affinity DataIC50: 120nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed