BDBM50468227 CHEMBL3581353

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]C1([#6])[#8]-c2cc3-[#8]-[#6@@H](-[#6]-[#6](=O)-c3c(-[#8])c2-[#6]=[#6]1)-c1cc(-[#8])cc(-[#8])c1

InChI Key InChIKey=VHRWNBKCPBRFSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50468227   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
The Czech Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50468227(CHEMBL3581353)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in leukotriene B4 production pre-incubated for 10 mins before arachidonic acid addition a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed