BDBM50468127 CHEMBL4288417

SMILES CCOc1cc(CN2CCC(CC2)c2ncc([nH]2)-c2ccc(F)cc2)cc(OCC)c1-c1ccc(F)cc1

InChI Key InChIKey=GOBNHYGEALNGCV-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50468127   

TargetSomatostatin receptor type 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50468127(CHEMBL4288417)
Affinity DataIC50: 7.60nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from human SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50468127(CHEMBL4288417)
Affinity DataIC50: 260nMAssay Description:Inhibition of MK-499 binding to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSomatostatin receptor type 5(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50468127(CHEMBL4288417)
Affinity DataIC50: 2.70nMAssay Description:Displacement of (3-125I-Tyr11)-SRIF-28 from mouse SSTR5 expressed in CHO-K1 cell membranes by filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSomatostatin receptor type 5(Mouse)
Merck

Curated by ChEMBL
LigandPNGBDBM50468127(CHEMBL4288417)
Affinity DataIC50: 98nMAssay Description:Antagonist activity at mouse SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSomatostatin receptor type 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50468127(CHEMBL4288417)
Affinity DataIC50: 247nMAssay Description:Antagonist activity at human SSTR5 expressed in CHO-K1 cell membranes assessed as reduction in SST-28-induced inhibition of forskolin-stimulated cAMP...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSomatostatin receptor type 3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50468127(CHEMBL4288417)
Affinity DataIC50: 119nMAssay Description:Antagonist activity at human SSTR3 expressed in CHO-K1 cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed