BDBM50466027 CHEMBL4292910

SMILES Oc1c(F)c(F)cc(C(=O)c2ccc(s2)-c2ccc3[nH]ccc3c2)c1F

InChI Key InChIKey=PDZDSJHULKVPPZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50466027   

Target17-beta-hydroxysteroid dehydrogenase type 2(Human)
Pharmbiotec

Curated by ChEMBL
LigandPNGBDBM50466027(CHEMBL4292910)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate after 20 mins in presence of NAD+ by radio-flow detector bas...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Pharmbiotec

Curated by ChEMBL
LigandPNGBDBM50466027(CHEMBL4292910)
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human placental cytosolic 17beta-HSD1 using [3H]-E1 as substrate after 10 mins in presence of NADPH by radio-flow detector based analys...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstradiol 17-beta-dehydrogenase 2(Mouse)
Pharmbiotec

Curated by ChEMBL
LigandPNGBDBM50466027(CHEMBL4292910)
Affinity DataIC50: 34nMAssay Description:Inhibition of mouse microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate after 20 mins in presence of NAD+ by radio-flow detector based analysi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed