BDBM50465457 Phantasmidine

SMILES [H][C@]12CC[C@]11Oc3nc(Cl)ccc3[C@]1([H])CN2

InChI Key InChIKey=CRXFCGUGNWJSEY-UHFFFAOYSA-N

Data  3 KI  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50465457   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Indiana State University

Curated by ChEMBL
LigandPNGBDBM50465457(Phantasmidine)
Affinity DataEC50:  5.60E+4nMAssay Description:Agonist activity at human alpha4beta2 nAChR by cell-based rubidium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
Indiana State University

Curated by ChEMBL
LigandPNGBDBM50465457(Phantasmidine)
Affinity DataEC50:  2.70E+4nMAssay Description:Agonist activity at rat alpha3beta4 nAChR by cell-based rubidium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Indiana State University

Curated by ChEMBL
LigandPNGBDBM50465457(Phantasmidine)
Affinity DataEC50:  2.10E+4nMAssay Description:Agonist activity at rat alpha7 nAChR expressed in Xenopus oocytes at -60 mV holding potential by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
Indiana State University

Curated by ChEMBL
LigandPNGBDBM50465457(Phantasmidine)
Affinity DataEC50:  45nMAssay Description:Agonist activity at rat alpha4beta2 expressed in Xenopus oocytes at -60 mV holding potential by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Indiana State University

Curated by ChEMBL
LigandPNGBDBM50465457(Phantasmidine)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]epibatidine from alpha4beta2 nAChR (unknown origin) expressed in HEK cell membranes after 4 hrs by liquid scintillation counting ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Indiana State University

Curated by ChEMBL
LigandPNGBDBM50465457(Phantasmidine)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]epibatidine from alpha7 nAChR (unknown origin) expressed in HEK cell membranes after 4 hrs by liquid scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
Indiana State University

Curated by ChEMBL
LigandPNGBDBM50465457(Phantasmidine)
Affinity DataKi:  390nMAssay Description:Displacement of [3H]epibatidine from alpha3beta4 nAChR (unknown origin) expressed in HEK cell membranes after 4 hrs by liquid scintillation counting ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed