BDBM50465399 CHEMBL4291940

SMILES Nc1ccccc1NC(=O)c1ccc(cc1)C(=O)NCCNc1nonc1\C(Nc1ccc(F)c(Br)c1)=N\O

InChI Key InChIKey=SVRNWBRVAJUUOX-UHFFFAOYSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50465399   

TargetHistone deacetylase 2(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465399(CHEMBL4291940)
Affinity DataIC50: 179nMAssay Description:Inhibition of HDAC2 (unknown origin) using substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465399(CHEMBL4291940)
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant human GST-tagged IDO1 (1 to 404 residues) using D-Tryptophan as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465399(CHEMBL4291940)
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant human full length HDAC1 using fluorogenic substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465399(CHEMBL4291940)
Affinity DataEC50:  410nMAssay Description:Inhibition of IDO1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine levels after 48 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 3(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465399(CHEMBL4291940)
Affinity DataIC50: 45nMAssay Description:Inhibition of HDAC3 (unknown origin) using substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 6(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465399(CHEMBL4291940)
Affinity DataIC50: 70nMAssay Description:Inhibition of HDAC6 (unknown origin) using substrate 3 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50465399(CHEMBL4291940)
Affinity DataIC50: 69nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
LigandPNGBDBM50465399(CHEMBL4291940)
Affinity DataIC50: 67nMAssay Description:Inhibition of HDAC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed