BDBM50465160 CHEMBL4284707
SMILES Cl.CN(C\C=C\C=C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2OCCOc2c1
InChI Key InChIKey=OBAUQDBJBFPVHQ-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50465160
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology
Curated by ChEMBL
East China University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...More data for this Ligand-Target Pair
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology
Curated by ChEMBL
East China University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of CrtN in vancomycin-intermediate Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophoto...More data for this Ligand-Target Pair
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain MW2))
East China University of Science and Technology
Curated by ChEMBL
East China University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 5.30nMAssay Description:Inhibition of CrtN in methicillin-resistant Staphylococcus aureus USA400 MW2 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrop...More data for this Ligand-Target Pair
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain MW2))
East China University of Science and Technology
Curated by ChEMBL
East China University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 3.70nMAssay Description:Inhibition of CrtN in methicillin-resistant Staphylococcus aureus LAC USA300 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrop...More data for this Ligand-Target Pair
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology
Curated by ChEMBL
East China University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of CrtN in linezolid-resistant Staphylococcus aureus NRS271 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotome...More data for this Ligand-Target Pair
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology
Curated by ChEMBL
East China University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 258nMAssay Description:Inhibition of Staphylococcus aureus Newman Hi6-tagged CrtN expressed in Escherichia coli BL21(DE3))/pET28a::CrtN assessed as reduction in staphyloxan...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
East China University of Science and Technology
Curated by ChEMBL
East China University of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of recombinant human ERG expressed in CHO cells at -80 mV holding potential measured after 3 minutes by automated whole cell patch clamp Q...More data for this Ligand-Target Pair