BDBM50465092 CHEMBL4287763::US11752138, Compound 137

SMILES Cc1ccc(cc1F)-c1cc(ccc1F)-c1nn(c(CC2CC2)c1Cc1ccc(c(F)c1)S(N)(=O)=O)-c1nc(cs1)C(O)=O

InChI Key InChIKey=WISPUGCBGDEBHD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465092   

TargetL-lactate dehydrogenase A chain(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465092(CHEMBL4287763 | US11752138, Compound 137)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of LDH (unknown origin) assessed as reduction in lactate production by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50465092(CHEMBL4287763 | US11752138, Compound 137)
Affinity DataIC50: 100nMAssay Description:This example describes a human LDHB biochemical assay employed in the characterization of a compound of Formula I in an embodiment of the dislcosure....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2023
Entry Details
Go to US Patent