BDBM50465089 CHEMBL4284356::US11752138, Compound 107

SMILES NS(=O)(=O)c1ccc(Cc2c(CC3CC3)n(nc2-c2ccc(F)c(c2)C2=CCC(F)(F)CC2)-c2nc(cs2)C(O)=O)cc1F

InChI Key InChIKey=SOJQTDIBDMTZJT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50465089   

TargetL-lactate dehydrogenase A chain(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50465089(CHEMBL4284356 | US11752138, Compound 107)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of LDH (unknown origin) assessed as reduction in lactate production by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Vanderbilt University

US Patent
LigandPNGBDBM50465089(CHEMBL4284356 | US11752138, Compound 107)
Affinity DataIC50: 100nMAssay Description:This example describes a human LDHB biochemical assay employed in the characterization of a compound of Formula I in an embodiment of the dislcosure....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2023
Entry Details
Go to US Patent