BDBM50464814 CHEMBL4281348

SMILES CCNc1cc(ccn1)-c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1C(F)(F)F

InChI Key InChIKey=BIIPWGFUTBPTNQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50464814   

TargetSerine/threonine-protein kinase PLK1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50464814(CHEMBL4281348)
Affinity DataIC50: 85nMAssay Description:Inhibition of full length human PLK1 using casein as substrate after 40 mins in presence of [gamma-33P]-ATP by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEukaryotic elongation factor 2 kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50464814(CHEMBL4281348)
Affinity DataIC50: 762nMAssay Description:Inhibition of GST-tagged EEF2K (unknown origin) using biotinylated EEF2 peptide substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetEukaryotic elongation factor 2 kinase(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50464814(CHEMBL4281348)
Affinity DataIC50: 760nMAssay Description:Inhibition of eEF2K (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed