BDBM50464534 CHEMBL4277951

SMILES CCCCCCC(CCCC(=O)Nc1ccccc1)CCC(=O)NO

InChI Key InChIKey=UXLCJJCZCBKZAI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50464534   

TargetHistone deacetylase 2(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464534(CHEMBL4277951)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of HDAC2 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464534(CHEMBL4277951)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of HDAC1 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464534(CHEMBL4277951)
Affinity DataIC50: 140nMAssay Description:Inhibition of HDAC6 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464534(CHEMBL4277951)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of HDAC3 in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 30 to 40 mins by fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464534(CHEMBL4277951)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of HDAC in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 35 mins by fluorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50464534(CHEMBL4277951)
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant full-length C-terminal His-tagged HDAC8 expressed in baculovirus infected Sf9 insect cell preincubated for 15 mins fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed