BDBM50464261 CHEMBL4292781

SMILES COc1ccc(Cl)cc1O[C@@H]1CN([C@@H]1C)S(=O)(=O)c1ccc2OCOc2c1

InChI Key InChIKey=JSEMZWQCXWGYNX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50464261   

TargetGlycine receptor subunit beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50464261(CHEMBL4292781)
Affinity DataEC50:  2.70E+3nMAssay Description:Positive allosteric modulation of human GlyRalpha3beta expressed in HEK293T cells assessed as increase in glycine-induced chloride ion flux measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed